Chemistry 320L/321L, Winter 2004                                                               Dr. Todor Gounev

CLASS MEETS:                                         Sec. V01 M    9:00 - 11:50 AM, SCB 217

                                                                  Sec. V02 W    9:00 - 11:50 AM, SCB 217

                                                                  Sec. V03 F      9:00 - 11:50 AM, SCB 217

Instructor:      Dr. Todor K. Gounev          Office:          510C Flarsheim Hall

Phone:             (816) 235-2294                    E-mail:         gounevt@umkc.edu

Teaching Assistants:  Sec. 1      Summer Campbell campbellsum@umkc.edu & Hamondeh Deeb deebh@umkc.edu

                                                Sec. 2      Summer Campbell campbellsum@umkc.edu & Hamondeh Deeb deebh@umkc.edu

                                                Sec. 3      Summer Campbell campbellsum@umkc.edu & Guang Liu liugua@umkc.edu

Office Hours:  Office hours will be announced in class by the GTAs.  Please come and see the instructor if there is a problem.

Co-requisites: Chemistry 320/321

Course objectives:  The objectives of this course are to teach basic organic laboratory technique and to provide experiences that will expand and enhance the student's scientific background.

Required text:  Zubrick, J.W. The Organic Chem Lab Survival Manual, 6th ed.; 2002.

Required materials: 

  • A lab notebook capable of making carbon copies. 
  • A padlock
  • Safety glasses
  • Black felt-tip pen with permanent ink (Sharpie)
  • Appropriate clothing

Class Attendance:  Attendance is required for all of the laboratory classes.  The class starts on time and finishes on time.  No makeup labs are allowed after the experiment has been completed.  Please observe the following:

  • Students must attend their assigned laboratory section.
  • Only substantial and unavoidable reasons (e.g., serious illness, unavoidable out-of-town professional travel, death in the family, religious observance, etc.) should cause students to miss a regularly scheduled lab.  Your instructor must be contacted at least 24 hours in advance of missing lab, and documentation must be provided.
  • Failure to notify your instructor at least 24 hours in advance or to provide documentation related to your reason for absence will result in forfeiture of the opportunity to perform the experiment; you will get a zero on the missed lab.

Pre-lab lecture and announcements:  All classes will convene in room C212 in the Spencer Chemistry Building before entering the lab for class announcements, pre-lab lecture, and to submit pre-lab questions and lab reports.

Glassware drawers:  You must provide a padlock for your glassware drawer.  You are responsible for maintaining the glassware clean and in good condition and for keeping your equipment drawer clean.  Even though you are expected to take appropriate care with equipment and glassware, it is reasonable to expect a small amount of breakage.  Notify the GTA as soon as possible if something is broken.  A breakage fee will be charged at checkout for all missing equipment.  No student will receive a grade for the course until he/she has checked-out and paid the breakage fee.

Pre-labs:  You are required to prepare a pre-lab before each experiment.  Your pre-lab work must be completed before you enter the laboratory.  Writing a pre-lab ensures that you have an understanding of your tasks during an experiment before you begin.  Ideally, the pre-lab should be thorough enough so that you can perform the experiment from what you have written without needing to refer to the handouts or to your book.  The GTAs collect a copy of the pre-lab along with your other notebook entries for the day.  You will not be allowed to perform the lab unless the pre-lab is complete.  The pre-lab should consist of the completed pre-lab questions in your handouts (collected at the beginning of class), and the following entries in your notebook (carbons collected as you leave lab):

  • Title:  Begin each experiment with a title, your name, the date, your GTA's name and your lab section.
  • Purpose:  A brief statement of the experimental objectives
  • Net equation and/or mechanism of reaction:  Include for all important reactions.
  • Table of quantities and physical constants:  Collect in tabular form the name, structure, molecular weight, density, melting or boiling point, solubility, mass or volume used, moles used, of any substance whose mass or volume you must measure.  Some of this information can be found in the handouts.  That which is not in the handouts can be looked up in The Aldrich Chemical Company Catalog, The Merck Index, The CRC Handbook of Chemistry and Physics, and on‑line at chemfinder.camsoft.com or webbook.nist.gov/chemistry.
  • Theoretical yield:  Calculate the theoretical yield of all reactions, showing all calculations.
  • Procedure:  Provide an outline of the experimental procedure to be carried out.  Do not simply copy what is written in the handouts; use your own words and diagrams.  It is often useful to construct a flow chart of the procedure. 

Lab notebooks: 

  • Read Chapter 2 in Zubrick.
  • Each experiment should begin on a new page.
  • Make every entry in your notebook in ink, never in pencil.  Don't erase or black out entries.  Instead, draw a line through the error and add the new information.
  • Record all laboratory observations and data directly in the lab notebook at the time they are observed.  Do not use scratch paper.  Do not expect to transcribe any information into the notebook at a later time.  Carbon copies of your notebook entries are handed in at the end of every laboratory session.
  • Organize your lab notebook using headings such as Title, Purpose, Procedure, Apparatus or Glassware set-up, Balanced reaction or Mechanism, Observations,  Purification, etc.

Lab reports:  The due dates for lab reports are listed in the class schedule accompanying the syllabus.  Lab reports must be turned in at the beginning of the pre-lab lecture prior to entering the laboratory.  Late lab reports will never be accepted.  No exceptions will be made.

  • For each experiment you will hand in (1) answers to pre-lab questions before beginning work,  (2) carbon copies of your lab notebook before leaving the lab, and (3) a completed post-lab report form on the scheduled due date.  These three items will be combined and graded. 
  • The individual lab handouts will be available for download at the course website, unofficial.umkc.edu/gounevt/Orgo320L/Organic.html.  Pre-lab questions appear before and post-lab report forms appear after the main body of each experiment in the lab handouts.
  • Your pre-lab questions and post-lab report must be typed using the Microsoft Word files provided on the website.  Chemical structures can be hand written. 

Grading:  You will be graded on the basis of nine lab reports and one exam.  Each report will be worth twenty points.  The exam is scheduled at the end of the class and will be worth forty points.  Grades will be assigned using the following scale:  90-100 = A;  80-89 = B;  70-79 = C;  60-69 = D;  0-59 = F.

Cheating:  Academic dishonesty will not be tolerated in this course.  Do not, under any circumstances, use fabricated data or data from another student.  Fabrication of data is academic misconduct: you will receive a grade of zero on the tainted work and will be reported to the Chief Academic Officer of your academic unit.

Grievance Procedures and Conduct of the Class:  Any grievance about grading and/or conduct of the class should be taken up first with the GTA.  If there is still a problem, then the student should talk with the Instructor.  Further comments and complaints should be addressed to the Chemistry Department Chair only after the Instructor has been consulted.  This class will be conducted in compliance with UMKC's Affirmative Action/Equal Opportunity and Sexual Harassment Policies (see UMKC General Catalog).


Tentative Schedule:  This schedule is tentative and subject to change during the course of the semester.  Any changes will be announced in class.  For lab handouts and other information go to the class website: unofficial.umkc.edu/gounevt/Orgo320L/Organic.html

Date

Topic

Sec. 1

Sec. 2

Sec. 3

 

1/12

1/14

1/16

Introduction, Laboratory Safety and Laboratory Check-in

1/19

1/21

1/23

Martin Luther King holiday (No Classes)

1/26

1/28

1/30

Crystallization

2/2

2/4

2/6

Crystallization

2/9

2/11

2/13

Distillation

[Crystallization laboratory report due]

2/16

2/18

2/20

Distillation

2/23

2/25

2/27

Extraction

[Distillation laboratory report due]

3/1

3/3

3/5

Extraction

3/8

3/10

3/12

Spring Break (No Classes)

3/15

3/17

3/19

Alkenes from Alcohols                                                 

[Extraction laboratory report due]

3/22

3/24

3/26

Friedel-Crafts Reaction

[Alkenes from alcohols laboratory report due]

3/29

3/31

4/2

Williamson Ether Synthesis

[Friedel-Crafts Reaction laboratory report due]

4/5

4/7

4/9

Grignard Reaction

[Williamson Ether Synthesis laboratory report due]

4/12

4/14

4/16

Aspirin Synthesis

[Grignard Reaction laboratory report due]

4/19

4/21

4/23

Aldol Condensation

[Aspirin Synthesis laboratory report due]

4/26

4/28

4/30

Checkout and Review for Test

[Aldol condensation laboratory report due]

5/3

5/3

5/3

Exam (1:00 – 3:00 pm)